Other oral diabetic medications

Class

Drug names

Can it cause hypoglycemia?

Alpha-glucosidase inhibitor: inhibits glucose absorption in intestine

Acarbose

No

DDP-inhibitor: decrease breakdown of incretin (regulates glucose levels)

Sitaliptin, Saxagliptin, Linaliptin

No

GLP-1 receptor agonist: acts like incretin hormone

Exenatide, Liraglutide

No

Sulfonylureas: stimulates insulin release from pancreas

Glicazide, Glyburide, Repaglinide

Yes

SGLT 2 inhibitor: blocks reabsorption of glucose in the kidney

Empagliflozin, Dapagliflozin, Canagliflozin

No

Thiazolidinedione: improves cell response to insulin

Pioglitazone, Rosiglitazone

No

  • Of the drugs on the above list, sulfonylureas are the most likely to be seen in Antigua and Barbuda
    • Sulfonylureas act by increasing the secretion of insulin from the pancreas
    • The most common side effect of sulfonylureas is low blood sugar (hypoglycemia)

References

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